Research & Innovation

Formulation development

Science-led innovation. Patient-focused design.

Aspen’s formulation development brings together pharmaceutical science and practical patient needs. We aim to develop dosage forms that address drug delivery, stability, palatability and ease of administration, with quality guiding every stage.

From conventional formulations to complex delivery platforms, our priorities centre on translating therapeutic requirements into well-designed products.

  • 250+Products in our range
  • 16Medical specialties
  • 6Dosage form categories
Gloved hands arranging capsules in a laboratory tray
Research focus

Core areas of formulation work

Five areas where our development effort is concentrated.

  1. 01

    Novel drug delivery systems

    Exploring delivery approaches that optimise how an active ingredient is released, according to its properties and intended use.

  2. 02

    Taste-masking technologies

    Addressing unpleasant taste through suitable formulation techniques, especially for oral liquids and dispersible preparations.

  3. 03

    Solubility and dissolution enhancement

    Improving the solubility and dissolution of poorly soluble active ingredients to support product performance.

  4. 04

    Modified-release formulations

    Sustained, extended or delayed-release strategies, guided by the active ingredient and the intended dosing profile.

  5. 05

    Bioequivalence and clinical evaluation

    Planning evidence-generation pathways, including bioequivalence studies and clinical trials where required, with qualified research partners and subject to regulatory requirements.

Dosage forms

Dosage forms we develop

Our formulation development spans pharmaceutical and nutraceutical dosage forms. See these forms in our product range by dosage form.

  • Oral solids

    Tablets, capsules, dispersible formulations and modified-release preparations.

  • Oral liquids

    Solutions, suspensions and emulsions, with attention to palatability and physical stability.

  • Sterile injectables

    Formulation considerations for injectable products, including compatibility, stability and suitability for sterile processing.

  • Topical preparations

    Creams, ointments and gels, with attention to consistency, application and drug release.

  • Hormonal formulations

    Product-specific considerations for dose uniformity, stability and appropriate manufacturing controls.

  • Nutraceuticals

    Formulations designed around ingredient compatibility, stability and convenient administration.

Complex oral formulations

Advanced tablet architectures

Our development priorities also include advanced tablet architectures. The choice of platform is guided by scientific feasibility and the needs of the intended product.

  • Two bilayer tablets showing separate layers

    Bilayer tablets

    Separate layers that can accommodate different ingredients or release profiles.

  • A broken tablet-in-tablet showing the core inside the outer tablet

    Tablet-in-tablet systems

    A core tablet within an outer tablet, enabling ingredient separation or tailored release.

  • Analyst handling a combination formulation sample beside a bottle

    Combination formulations

    Multiple active ingredients developed with attention to compatibility, stability and dosage requirements.

Our development approach

Five stages from concept to evidence

  1. Understand the product

    Evaluate the active ingredient, intended dosage form, patient needs and target product characteristics.

  2. Design the formulation

    Select suitable excipients and explore formulation options through structured development trials.

  3. Evaluate performance

    Assess relevant attributes such as dissolution, release behaviour, uniformity, compatibility and stability.

  4. Prepare for scale-up

    Consider process reproducibility, manufacturing suitability and technology-transfer requirements.

  5. Build the evidence

    Define the analytical, stability and study requirements needed to support the applicable development and regulatory pathway.

Quality built into development

Practical to manufacture, consistent in performance

A successful formulation must be practical to manufacture and consistent in performance. We emphasise scientifically justified ingredient selection and documented evaluation.

Discuss your formulation requirements